The United States is Canada’snumber onetrading partner, and Canada is America’ssecond largest. However, to what extent does the amount of trade between these two nations span? The Great Lakes Region is composed of the two Canadian provinces of Ontario and Quebec, and the eight states of Michigan, New York, Ohio, Pennsylvania, Minnesota, Wisconsin, Illinois, and Indiana. The Gross Domestic Product of the Great Lakes Region is$6 trillion, which means that if the region were a country, it would be the third largest economy right behind the United States and China.$278 billion dollarsof bilateral trade is generated in the Great Lakes Region each year, and there is a highly integrated supply chain in order to sustain such a massive amount of exports and imports.